In a recent study, it has been noticed that a natural compound found in grape seed extract may help prevent tooth decay.
The grape seed extract can strengthen dentin – the tissue beneath a tooth’s enamel which comprises the majority of the calcified extracellular tissue of teeth, forming the layer just beneath the hard external enamel.
It can also make composite-resin fillings stronger, allowing them to last longer.
Ana Bedran-Russo, associate professor at University of Illinois at Chicago (UIC) in the US said, “One of the possible benefits of using grape seed extract is that it prevents tooth decay.”
Bedran-Russo added, “Dentin is mostly made of collagen, the main structural protein in skin and other connective tissues. Resins have to bind to the dentin, but the area between the two, or the interface, is a weak point, causing restorations to breakdown.”
It was discovered during the study that spoiled collagen can mend itself with a combination of plant-based oligomeric proanthocyanidins – flavonoids found in most foods and vegetables – and extracts from grape seeds.
The study also depicted that Interlocking the resin and collagen-rich dentin provides better adhesion and does not rely on moisture.
Bedran-Russo said, “When fillings fail, decay forms around it and the seal is lost. We want to reinforce the interface, which will make the resin bond better to the dentin. The interface can be changed through the use of new natural materials.”
“The stability of the interface is key for the durability of such adhesive joints, and hence, the life of the restoration and minimising tooth loss,” he added.
The study was published in Journal of Dental Research.